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Proteomics, a dynamic field of study, is significantly influenced by post-translational modifications (PTMs). These modifications play a crucial role in finely tuning protein structure, function, stability, cellular localization, and enzymatic activity. Among these, citrullination, a specific PTM, involves the conversion of arginine residues into citrulline through an enzymatic reaction mediated by peptidylarginine deiminase (PAD) family…
Current mechanistic research endeavors are dedicated to exploring various molecular dimensions, including genomics, epigenomics, transcriptomics, proteomics, and metabolomics, aiming to provide a comprehensive elucidation of biological processes through diverse technical approaches. Among these processes, post-translational modifications (PTMs) of proteins, such as phosphorylation, glycosylation, methylation, ubiquitination, lactylation, and palmitoylation, are pivotal. These modifications play central roles…
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