Exosomes are natural nanoparticles containing biologically active molecules, which are important mediators of intercellular communication and can be used for therapeutic purposes through various bioengineering approaches. In addition to isolating, characterizing, and engineering exosomes, choosing the appropriate route of administration and dosage is an important parameter for achieving the clinical relevance of exosomes. Currently, intravenous (IV) infusion is the most common mode of exosome administration.
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